A Pilot Treatment Study for Mild Traumatic Brain Injury: Neuroimaging Changes Detected by Meg After Low-Intensity Pulse-Based Transcranial Electrical Stimulation
Brain Injury & Micro Current Neurofeedback
Background: Mild traumatic brain injury (mTBI) is a leading cause of sustained impairments in military service members, Veterans, and civilians. However, few treatments are available for mTBI, partially because the mechanism of persistent mTBI deficits is not fully understood.
Methods: We used magnetoencephalography (MEG) to investigate neuronal changes in individuals with mTBI following a passive neurofeedback-based treatment program. This program involved applying low-intensity pulses using transcranial electrical stimulation (LIP-tES) with electroencephalography monitoring.
Results: At the baseline MEG exam, all participants had abnormal slow-waves. In the follow-up MEG exam, the participants showed significantly reduced abnormal slow-waves with an average reduction of 53.6 ± 24.6% in slow-wave total score. The participants also showed significant reduction of PCS scores after treatment, with an average reduction of 52.76 ± 26.4% in PCS total score.
Conclusions: The present study demonstrates, for the first time, the neuroimaging-based documentation of the effect of LIP-tES treatment on brain functioning in mTBI. The mechanisms of LIP-tES treatment are discussed, with an emphasis on LIP-tES’s potentiation of the mTBI healing process.
Clinical Studies & Trials
1. Anti-Inflammation. Laser therapy has an anti-edemic effect (reduction in swelling caused by bruising or inflammation).
2. Anti-Pain (Analgesic). Laser therapy may block pain and decrease nerve sensitivity.
3. Accelerated Tissue Repair And Cell Growth. Laser light can increase the energy available to the cell so that the cell can take on nutrients faster and get rid of waste products. As a result tendons, ligaments and muscles are repaired faster.
4. Improved Vascular Activity. Laser light can increase the formation of new capillaries in damaged tissue that speeds up the healing process, closes wounds quickly and reduces scar tissue.
5. Increased Metabolic Activity. Laser therapy creates higher outputs of specific enzymes, greater oxygen and food particle loads for blood cells.
6. Trigger Points and Acupuncture Points. Laser therapy stimulates muscle trigger points and acupuncture points on a non-invasive basis providing musculoskeletal pain relief.
7. Reduced Fibrous Tissue Formation. Laser therapy reduces the formation of scar tissue following tissue damage from cuts, scratches, burns or surgery.
8. Improved Nerve Function. Laser light can speed up the process of nerve cell reconnection and increase the amplitude of action potentials to optimize muscle action.
9. Immunoregulation. Laser light has can stimulate immunoglobines and lymphocytes. The enzyme flavomono-nucleotide is activated and starts the production of ATP (adenosine-tri-phosphate), which is the major carrier of cell energy and the energy source for all chemical reactions in the cells.
10. Faster Wound Healing. Laser light stimulates wound healing in damaged tissue.
The Lancet report says:
"(relief using)... laser for neck pain lasted for up to 22 weeks. Trials of LLLT for knee osteoarthritis tendinopathies and low back pain reported similar results... "This contrasts with drug therapies where the effect ends rapidly when treatment is discontinued."
· Reduce pain intensity
· Reduced disability
· Reduces recurrence of acute neck pain
· Mean Pain intensity reduction over placebo 20mm (95%CI: 17.1 to 29.8 @ 10-22 weeks)
THOR LLLT presentation at United Nations – Global Health Impact Forum
An overview of Photobiomodulation and low level light therapy at the United Nations. A treatment for Dry Age related Macular Degeneration (AMD) is also discussed.
PTSD / TBI
The VA, Boston University and Harvard Medical School published the results of a Transcranial LLLT (LED) pilot study on mild Traumatic Brain Injury (TBI). Incredibly; TBI is a leading cause of death and disability among children and young adults in the United States. This study showed significant improvement in Executive Function, Verbal Learning, Long Delay Free Recall and fewer post-traumatic stress disorder (PTSD) symptoms. Participants and family reported better ability to perform social, interpersonal, and occupational functions.
Role of Low-Level Laser Therapy in Neurorehabilitation
“LLLT (low level light therapy) is steadily moving into mainstream medical practice…LLLT has no reported adverse effects, and no reports of adverse events can be directly attributed to laser or light therapy…Moreover, the particular benefits of LLLT to both the central and peripheral nervous systems suggest that much wider use of LLLT could or should be made in cases of both brain diseases and injuries.”
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