What is CES?


Cranial electrical stimulation (CES) therapy involves the use of a small, battery-operated device that delivers low levels of alternating electrical current to the head via clips that are attached to the earlobes. 

CES therapy has had positive effects on the treatment of sleep disturbances, depressive symptoms, perceived stress, and other disorders in a variety of patient populations.  

Medical Research Relief from Insomnia, Anxiety & Depression

Review of Effective Non-Drug Treatments Utilized by 3Calm

Nutrition - Step One of the 3Calm System

GABA levels (gamma-aminobutyric acid) are shown to play role in severe depression.  The study of GABA may lead to the next advance in treating major depression.  This study shows that compared to healthy individuals, people who have major depressive disorder have the greatest reduction in GABA levels.     GABA Supplement


Neuropharmacology - The GABA system in anxiety and depression and its therapeutic potential

Audio - Step Two of the 3Calm System

Audio entrainment, as isochronic tones, is an effective, low cost treatment with apparently few to no side effects and requires no special training or expertise; it can be used whenever and wherever needed.  Audio technology treats anxiety with isotronic tones

CES -  Cranial Electrotherapy Stimulation - Step 3 of the 3Calm System

Anxiety, Depression & Insomnia

Cranial electrotherapy stimulation (CES) is a US Food and Drug Administration–approved, prescriptive, noninvasive electromedical treatment that has been shown to decrease anxiety, insomnia, and depression significantly.

CES significantly decreases anxiety and comorbid depression. Subjects reported no adverse events during the study.  

CES Meta-analysis indicates a moderate to strong positive results in treating depression which exceed the results of drug studies submitted to the FDA for marketing approval.

Graphic results indicating cranial electrotherapy stimulation (CES) is effective in reducing symptoms of Depression Patients and Mixed Anxiety Depressive Disorder.

In this experiment involving children with emotional disorders the change in emotions was fast and significant; the emotions turned significantly better 3~5 days or 7~10 days after the treatment; the patients were in good moods, which could be seen from their body language without much conversation. In the whole process of the treatment, the patients were active with good compliance and without fear and resistance. After the treatment, the SAS and SDS scores both dropped significantly, reaching or close to the normal values, and the difference is significant.


Cranial Electrotherapy Stimulation (CES) is an effective, established treatment for insomnia while simultaneously reducing anxiety, depression and pain.

A randomized, double-blind, and placebo controlled clinical trial found cranial electric stimulation for the treatment of insomnia a significant increase in total time slept after three cranial electric stimulation treatments among all study subjects. 

Graphic results indicating cranial electrotherapy stimulation (CES) is effective in reducing symptoms of Generalized Anxiety Disorder, Mixed Anxiety Depressive Disorder, Preoperative Anxiety and Dental Anxiety.

A double-blind placebo-controlled study was performed on 33 randomly selected dental patients to evaluate whether cranial electrotherapy stimulation (CES) is a viable procedure for reducing anxiety during routine dental procedures. The active CES treatment group was significantly less anxious than the placebo group at the conclusion of various dental procedures.


Addictions are serious and poorly understood problems that may involve prescribed or illicit drugs, alcohol, or compulsive behavioral patterns involving sex, gambling, eating or “surfing the net." Cranial electrotherapy stimulation (CES) has been shown in 15 studies to quickly, safely and effectively reduce the physical withdrawal, psychological cravings and co-morbid anxiety, insomnia and depression in people suffering from addictive disorders.

Cranial electrotherapy stimulation (CES) has been shown in 15 studies to quickly, safely and effectively reduce the physical withdrawal, psychological cravings and co-morbid anxiety, insomnia and depression in people suffering from addictive disorders.


Study to evaluate CES to control cigarette cravings. Elimination of cravings in a single trial was nearly universal.

All CES patients in this hospital detoxification and rehabilitation program for cocaine dependent persons completed rehab. No side effects were reported.


In this preliminary study we found that the use of CES was safe and feasible in advanced cancer patients. The use of CES was associated with significant improvement of depression, anxiety, pain, and sleep scores. These findings support further studies of CES in ACP for symptom control.


Microcurrent cranial electrical stimulation (CES) therapy effectively treats pain


The American Society for Pain Management Nursing found cranial electrical stimulation (CES) improves symptoms and functional status in individuals with fibromyalgia. Those individuals using the active CES device had a greater decrease in average pain, fatigue, and sleep disturbance than individuals using the sham device or those receiving usual care alone over time. Additionally, individuals using the active CES device had improved functional status.

Positive results from recent studies suggest that CES may provide the relief from symptoms of fibromyalgia that nothing else has. Patients use CES by clipping electodes to their earlobes which transmit electricity directly through the brain. Unlike with the use of medication, there is no ongoing cost for the use of the CES device. Lichtbroun concluded that CES is as effective as the drug therapies, with no negative side effects.


The Journal of Rehabilitation Research and Development found in a study of veterans that prior treatments for chronic pain in persons with spinal cord injury (SCI) have not been effective. The study was a double-blind, sham controlled design with random assignment examining the effects of daily one hour active (N = 18) or sham (N = 20) CES treatments for 21 consecutive days on pain intensity and interference activities in 38 male veterans who had received care at a Department of Veterans Affairs spinal cord injury (SCI) Center. Treatments were self administered at home. The active cranial electrotherapy stimulation (CES) group reported significantly decreased daily pain intensity (p = 0.03) compared with the sham CES group. The active CES group also showed significantly decreased pain interference (p = 0.004).

Cranial electrotherapy stimulation (CES) is being prescribed for service members and veterans for the treatment of anxiety, posttraumatic stress disorder (PTSD), insomnia and depression. CES provides service members and veterans with a safe, noninvasive, nondrug, easy to use treatment for anxiety, PTSD, insomnia, and depression that can be used in the clinical setting or self-directed at home.

Practical Pain Management calls CES stimulators safe and effective for mild traumatic brain injury


CES therapy is a viable intervention to test in dementia–care dyads as an aid in reducing sleep disturbances and depressive symptoms and improving quality of life. 

Weighted Blankets


This paper studied the safety and effectiveness of the use of a 30 lb weighted blanket and found that weighted blankets are safe and 63% reported lower anxiety after use, and 78% preferred the weighted blanket as a calming modality. Key Words: Sensory modulation, weighted blanket, deep pressure touch stimulation, skin conductance, electrodermal activity